the goodDEMAND podcast
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the goodDEMAND podcast
Seamus Sullivan: Longevity, Health and Fitness #36
On this episode of the GOODDEMAND podcast, we sit down with a longevity expert and performance health coach to break down the real science behind living longer, stronger, and healthier—without the gimmicks.
We talk about the difference between health, fitness, and longevity, and why optimizing for one can sometimes compromise the others. We explore core strategies like diet, sleep, muscle mass, VO2 max, mental health, and social connection, plus cutting-edge topics like plasma exchange therapy, blue zones, red light, biohacking, and Brian Johnson’s blueprint lifestyle.
This conversation is perfect for anyone curious about personal development, biohacking, anti-aging, or just wanting to live better. No fluff—just actionable science and expert coaching insights.
Questions Answered in This Episode:
- What’s the difference between fitness, health, and longevity?
- Does muscle mass actually make you live longer?
- What diet is best for anti-aging and long-term performance?
- How does VO2 max predict your healthspan and lifespan?
- Can red light, sleep tracking, or blue light blocking really work?
- What’s the deal with plasma exchange therapy and Brian Johnson’s longevity protocol?
- How do you stay consistent with protein intake and workouts?
- Why are social connection and purpose vital for your health?
Timestamps:
00:00 – Intro + What really defines longevity vs. health vs. fitness
04:15 – Is 80% of lifespan lifestyle-based?
07:10 – Muscle mass, bone health & falling risk in aging
10:00 – VO2 max, healthspan, and performance synergy
13:40 – Diet for longevity: Blue zones, protein, fasting & real-world application
21:00 – Plant-based vs. high-protein: What works best and why
28:20 – How to consistently hit your protein targets
33:00 – The dangers of going "all-in" on bulking or shredding
36:40 – The problem with over-optimizing gut health
41:00 – Peter Attia's cardio protocol and the role of VO2 max
46:00 – HIIT vs. Zone 2: Which is better for busy professionals?
51:30 – Brain health, BDNF & why movement boosts cognition
55:00 – Sleep: Why it's the most underrated biohack
58:20 – Shift workers, circadian rhythms & practical sleep solutions
1:03:00 – Brian Johnson: Longevity pioneer or outlier?
1:08:10 – Plasma exchange therapy & blood transfusions explained
1:12:00 – Lifestyle medicine: Science vs. spirituality & being human
1:16:40 – Food deserts, systemic inequality & wellness access
1:21:30 – Building community, purpose, and mindset for a longer life
1:26:00 – Final takeaways: Why you’re one decision away from change
Resources Mentioned:
- Podcast Guest: Seamus Matthew Sullivan
- Synogenics (Longevity Clinic): https://www.synogenics.com
- Seamus’ Coaching Program: DM Seamus on Instagram for coaching
- The Macro Perspective Podcast: Available on all platforms
Subscribe now for more episodes on longevity, fitness, self-development, and modern health optimization.
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